Enhancing Biotherapeutic Stability: CARBOGEN AMCIS Featured in PharmTech eBook

Caroline Ailhas, our Pharmaceutical Development Director, contributed her expertise to the recent PharmTech article titled “Prioritizing Formulation Strategies for Temperature-Sensitive Biotherapeutics.”

This article, featured in the September 2024 Trends in Formulation eBook, highlights the evolving strategies required to enhance the stability of biopharmaceuticals, particularly those sensitive to temperature variations, such as antibodies and mRNA-based vaccines.

Caroline's insights (page 6) emphasize the significant challenges in maintaining the molecular structure and functionality of temperature-sensitive biotherapeutics. Her contribution underscores the importance of determining stabilization duration—ranging from a few days to several months, or even years—depending on the specific requirements of the drug's development and storage. This variable plays a crucial role in shaping the overall formulation strategy.