Speciality Chemicals Magazine: CARBOGEN AMCIS featured on High Potency APIs

CARBOGEN AMCIS has been featured in the latest edition of Speciality Chemicals Magazine. In an article entitled "Beyond the lab: Efficient strategy for kilogram-scale HPAPI handling" Patrick Gay Manager of PR&D and Julien Perron Senior Chemist describe state-of-the-art strategies and investments required for handling high potency active pharmaceutical ingredients at a kilogram scale.

Safety and Efficiency in HPAPI Handling

The paper indicates that HPAPIs play an important role in the pharmaceutical industry particularly in oncology since quite often they exert high biological activity at very low dosages. The same potency simultaneously demands rigorous safety measures and calls for specialized facilities to handle such substances without risking exposure. Patrick Gay and Julien Perron describe the equipment and procedures CARBOGEN AMCIS uses to meet these stringent requirements.

State-of-the-Art Infrastructure and Work Flow

The processes of the workflows at CARBOGEN AMCIS are described—from the extractions to the end production stages—in the article. Some important parts in our infrastructure are walk-in fume hoods (WFH) and glovebox systems.

• Walk-in Fume Hoods: Highly controlled non-recirculating airflow systems are fitted with features that maintain the low OEL.
• Glovebox Systems: HEPA filters and several other safety parameters are fitted ensuring operators' safe working conditions while handling HPAPI compounds.
• Nitrogen Overpressure: Applied to the glovebox to further reduce the risk of contamination.

We also shed light on our recent upgrades in lab-scale HPAPI production facilities which mirror our commitments toward making improvements in safety and efficiency; these include improved glovebox technology and new fume hood additions designed for kilogram-scale campaigns.

Commitment to Quality and Safety

Quality and safety are catalyzed at CARBOGEN AMCIS. The article underlines our adherence to the standards of safety ensuring that the processes meet or excel according to the industrial requirements. Meticulous planning sophisticated technology and highly trained teams work in perfect harmony to offer top-tier HPAPI handling and production services.